A lumbar puncture is performed on a 40-year-old man experiencing symptoms of blurred vision and numbness in his extremities.Results are:
-Based on the information provided,what abnormality is present in the CNS of this patient if the IgG index is calculated to be above 0.70?

Question

A lumbar puncture is performed on a 40-year-old man experiencing symptoms of blurred vision and numbness in his extremities.Results are: 
-Based on the information provided,what abnormality is present in the CNS of this patient if the IgG index is calculated to be above 0.70?

Quizplus · Accepted Answer

If the IgG index is above 0.70, it indicates an increased level of IgG in the cerebrospinal fluid compared to the blood. This is often seen in conditions where there is neural IgG synthesis, such as multiple sclerosis or other autoimmune disorders affecting the central nervous system. CSF leakage, decreased blood-brain barrier integrity, and bacterial meningitis would not necessarily be indicated by an elevated IgG index.

A Lumbar Puncture Is Performed on a 40-Year-Old Man Experiencing