In General,when Will the FDA Require Prescription Use of a Drug

In general,when will the FDA require prescription use of a drug?

A) If the drug is toxic,requires a physician's supervision for safe use,or is addictive
B) Only if the drug is toxic
C) Only if the drug is either toxic or requires a physician's supervision for safe use
D) Only if the drug is addictive or requires a physician's supervision for safe use