How does ChR2 activate neurons? A) Blue light causes a conformational change in a rhodopsin protein which causes the channel to open. This results in a nonselective cation current that allows more Na⁺ influx than K⁺ efflux, depolarizing the neuron. B) Blue light causes a conformational change in a rhodopsin protein which causes the channel to open. This results in a nonselective cation current that allows more K⁺ efflux than Na⁺ influx, depolarizing the neuron. C) Blue light activates the rhodopsin protein that activates a G protein which opens a nonselective cation current which allows more Na⁺ influx than K⁺ efflux, depolarizing the neuron. D) Blue light activates the rhodopsin protein that activates a G protein which opens a nonselective cation current which allows more Na⁺ influx than K⁺ efflux, hyperpolarizing the neuron. E) Blue light activates the rhodopsin protein that activates a G protein which opens a nonselective cation current which allows more K⁺ efflux than Na⁺ influx, depolarizing the neuron. F) Blue light activates the rhodopsin protein that activates a G protein which opens a nonselective cation current which allows more K⁺ efflux than Na⁺ influx, hyperpolarizing the neuron.

Question

Quizplus · Accepted Answer

The channel rhodopsin (ChR2) protein is an ion channel that is permeable to potassium and sodium but is more permeable to sodium and so the reversal potential is more depolarized than action potential threshold so opening the channel is excitatory.

How Does ChR2 Activate Neurons