Which of the following conditions would be expected to correlate with an increase in circulating testosterone from exogenous androgenic steroid use (for example, by athletes)?
A) An increase in LH/FSH release by the anterior pituitary
B) An increase in GnRH release by the hypothalamus
C) An increase in Kiss1 release by the arcuate nucleus
D) An increase in secondary sex characteristics such as muscle mass, body hair, and aggression
E) An increase in testis size

Question

Quizplus · Accepted Answer

Circulating testosterone and estradiol exert negative feedback on the KissI neurons for homeostatic regulation of GnRH release. Excess circulating testosterone would lower Kiss1 release, GnRH release, and LH/FSH release. This would result in hypogonadism even though secondary sexual characteristics would be masculinized by the androgens.

Which of the Following Conditions Would Be Expected to Correlate