If SCN neurons are dissociated from each other and put in cell culture, what happens to the timing of Per expression? Choose all that apply.
A) Expression of Per in individual neurons remains circadian.
B) Per expression in all the dissociated neurons continue to oscillate in the same phase.
C) Expression of Per in individual neurons does not oscillate.
D) Per expression in all the dissociated neurons is completely reduced because there is no neuropeptide signaling.

Question

Quizplus · Accepted Answer

When SCN neurons are dissociated from each other and put in cell culture, individual neurons maintain the ability to express Per in a circadian manner. However, the synchronization between neurons that occurs in vivo is lost, so the timing of Per expression in each neuron may not be the same.

If SCN Neurons Are Dissociated from Each Other and Put