A series of critical experiments showed the properties of chemical synaptic transmission at the neuromuscular junction. One of these is shown in Figure Q3-1 in which the voltage across the membrane was recorded with an intracellular electrode. Figure Q3-1
A. What happened when the motor axon was stimulated?
B. The investigators then applied ACh to the muscle via iontophoresis in the presence of TTX. Why did they use TTX?
C. The elicited response of ACh iontophoresis was similar to nerve stimulation. What did this tell the investigators?

Question

A series of critical experiments showed the properties of chemical synaptic transmission at the neuromuscular junction. One of these is shown in Figure Q3-1 in which the voltage across the membrane was recorded with an intracellular electrode.  Figure Q3-1
A. What happened when the motor axon was stimulated?
B. The investigators then applied ACh to the muscle via iontophoresis in the presence of TTX. Why did they use TTX?
C. The elicited response of ACh iontophoresis was similar to nerve stimulation. What did this tell the investigators?

Quizplus · Accepted Answer

The Answer of A series of critical experiments showed the properties of chemical synaptic transmission at the neuromuscular junction. One of these is shown in Figure Q3-1 in which the voltage across the membrane was recorded with an intracellular electrode.  Figure Q3-1
A. What happened when the motor axon was stimulated?
B. The investigators then applied ACh to the muscle via iontophoresis in the presence of TTX. Why did they use TTX?
C. The elicited response of ACh iontophoresis was similar to nerve stimulation. What did this tell the investigators?

A Series of Critical Experiments Showed the Properties of Chemical