Endocrine diseases are often due to loss of hormone (i.e.,a hormone deficiency).Which of the following would cause an endocrine disease that mimicked a protein hormone deficiency without a deficiency in the levels of a circulating protein hormone?
A)Inactive prohormone convertase
B)Defective exocytotic machinery
C)Loss of blood transport proteins
D)Defective receptor
E)Null mutation in corresponding hormone gene

Question

Quizplus · Accepted Answer

A defective receptor would prevent the hormone from exerting its effects, mimicking a hormone deficiency, even though the hormone levels are normal.

Endocrine Diseases Are Often Due to Loss of Hormone (I