Question 1

What is the missing reactant in the following reaction?

Accepted Answer

C

Question 2

Which of the following statements is not true about a carbene?

Accepted Answer

A carbene is actually sp2 hybridized with two unshared electrons or a lone pair on the divalent carbon.

Question 3

Which of the following correctly describes a reaction yielding a dichorocarbene?

Accepted Answer

The reaction of chloroform with a strong base like potassium tert-butoxide (KOC(CH3)3) generates dichlorocarbene, a reactive intermediate used in organic synthesis.

Question 4

Which of the reactions listed below is not stereospecific?

Accepted Answer

The answer of Which of the reactions listed below is...

Question 5

Which statement below best explains what is meant by the statement,"An organocuprate reaction with a vinyl halide is stereospecific"?

Accepted Answer

The statement that an organocuprate reaction with a vinyl halide is stereospecific means that the reaction preserves the stereochemistry of the starting material. Thus, if a specific stereoisomer is used as the starting material, the product will also be that same stereoisomer, reflecting the preservation of stereochemistry through the reaction.

Question 6

Which class of compounds listed below does not react with organocuprate reagents to form a coupling product that contains a new carbon-carbon bond?

Accepted Answer

Organocuprate reagents typically do not react with tertiary (3°) alkyl halides to form coupling products because the steric hindrance around the tertiary carbon center makes it difficult for the nucleophilic organocuprate to attack and form a new carbon-carbon bond.

Question 7

What products are formed when diazomethane is heated?

Accepted Answer

When diazomethane is heated, it decomposes into methylene, a reactive carbene, and nitrogen gas.

Question 8

What is the major organic product of the following reaction?

Accepted Answer

The answer of What is the major organic product of...

Question 9

Which of the following statements is not true about the Simmons-Smith reaction?

Accepted Answer

The Simmons-Smith reaction does not involve the formation of a free carbene; instead, it generates an organozinc carbenoid intermediate.

Question 10

Organocuprate reagents (R₂CuLi)react with several compounds.Which listed reaction is not correct?

Accepted Answer

Carbon dioxide does not react with organocuprate reagents to form carboxylic acids. Instead, it reacts to form carboxylic acid salts.

Question 11

What do the Suzuki reaction,the Heck reaction,and the organocuprate reaction all have in common when they react with an alkyl halide?

Accepted Answer

The Suzuki reaction, the Heck reaction, and the organocuprate reaction all involve the formation of a new carbon-carbon bond when reacting with an alkyl halide.

Question 12

What is the major organic product of the following reaction?

Accepted Answer

The answer of What is the major organic product of...

Question 13

Identify the products of the following reaction.

Accepted Answer

The answer of Identify the products of the following reaction....

Question 14

Identify the products of the following reaction.

Accepted Answer

The product of the reaction is compound B, which is formed by the addition of ethylamine to acetyl chloride. None of the other compounds are formed by this particular reaction.

Question 15

Choose the statement below that is not true about the Suzuki reaction.

Accepted Answer

The Suzuki reaction forms more highly substituted alkenes.

Question 16

Which of the following is not a step in the Suzuki reaction?

Accepted Answer

The Suzuki reaction involves the cross-coupling of an organoboron compound with a halide using a palladium catalyst. The steps include oxidative addition, transmetalation (where the alkyl group is transferred from the organoborane to palladium, not substitution), and reductive elimination. Substitution of the R group to the palladium catalyst is not a recognized step in this process.

Question 17

Which of the following is true about the use of the Grubbs catalyst?

Accepted Answer

The Grubbs catalyst is specifically used in alkene metathesis, which involves the exchange of substituents between two alkenes. It does not involve carbon-carbon coupling reactions or carbene formation. Palladium is not typically used as a co-catalyst with the Grubbs catalyst.

Question 18

Coupling reactions with vinyl halides are stereospecific.Which choice below best describes the expected product when trans-1-bromo-1-hexene reacts with (CH₃)₂CuLi?

Accepted Answer

When coupling reactions with vinyl halides occur, they typically follow the stereospecific rules of syn-addition, meaning that the new substituents are added to the same side of the molecule. In this case, trans-1-bromo-1-hexene has a trans double bond, meaning that the two substituents on each carbon are on opposite sides. When the vinyl halide reacts, it will add its two substituents to the same side of the molecule, leading to a trans-alkene. Therefore, the expected product will only yield a trans-alkene.

Question 19

Which of the following descriptions does not apply to methylene?

Accepted Answer

Methylene is a neutral, reactive intermediate, and its formula is :CH2. It is not a radical intermediate.

Question 20

What is the major organic product of the following reaction?

Accepted Answer

The answer of What is the major organic product of...

Quiz 24: Carbon-Carbon Bond-Forming Reactions in Organic Synthesis

What is the missing reactant in the following reaction?

Which of the following statements is not true about a carbene?

Which of the following correctly describes a reaction yielding a dichorocarbene?

Which of the reactions listed below is not stereospecific?

Which statement below best explains what is meant by the statement,"An organocuprate reaction with a vinyl halide is stereospecific"?

Which class of compounds listed below does not react with organocuprate reagents to form a coupling product that contains a new carbon-carbon bond?

What products are formed when diazomethane is heated?

What is the major organic product of the following reaction?

Which of the following statements is not true about the Simmons-Smith reaction?

Organocuprate reagents (R₂CuLi) react with several compounds.Which listed reaction is not correct?

What do the Suzuki reaction,the Heck reaction,and the organocuprate reaction all have in common when they react with an alkyl halide?

What is the major organic product of the following reaction?

Identify the products of the following reaction.

Identify the products of the following reaction.

Choose the statement below that is not true about the Suzuki reaction.

Which of the following is not a step in the Suzuki reaction?

Which of the following is true about the use of the Grubbs catalyst?

Coupling reactions with vinyl halides are stereospecific.Which choice below best describes the expected product when trans-1-bromo-1-hexene reacts with (CH₃) ₂CuLi?

Which of the following descriptions does not apply to methylene?

What is the major organic product of the following reaction?

Quiz 24: Carbon-Carbon Bond-Forming Reactions in Organic Synthesis

What is the missing reactant in the following reaction?

Which of the following statements is not true about a carbene?

Which of the following correctly describes a reaction yielding a dichorocarbene?

Which of the reactions listed below is not stereospecific?

Which statement below best explains what is meant by the statement,"An organocuprate reaction with a vinyl halide is stereospecific"?

Which class of compounds listed below does not react with organocuprate reagents to form a coupling product that contains a new carbon-carbon bond?

What products are formed when diazomethane is heated?

What is the major organic product of the following reaction?

Which of the following statements is not true about the Simmons-Smith reaction?

Organocuprate reagents (R2CuLi) react with several compounds.Which listed reaction is not correct?

What do the Suzuki reaction,the Heck reaction,and the organocuprate reaction all have in common when they react with an alkyl halide?

What is the major organic product of the following reaction?

Identify the products of the following reaction.

Identify the products of the following reaction.

Choose the statement below that is not true about the Suzuki reaction.

Which of the following is not a step in the Suzuki reaction?

Which of the following is true about the use of the Grubbs catalyst?

Coupling reactions with vinyl halides are stereospecific.Which choice below best describes the expected product when trans-1-bromo-1-hexene reacts with (CH3) 2CuLi?

Which of the following descriptions does not apply to methylene?

What is the major organic product of the following reaction?

Organocuprate reagents (R₂CuLi) react with several compounds.Which listed reaction is not correct?

Coupling reactions with vinyl halides are stereospecific.Which choice below best describes the expected product when trans-1-bromo-1-hexene reacts with (CH₃) ₂CuLi?