Question 1

An individual who has the genotype X^NXⁿ for night blindness is considered a ________ for night blindness.

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Question 2

X-linked disorders more commonly affect males than females because males have only one ________ chromosome.

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Question 3

Researchers hope to develop treatments for sex-linked genetic disorders such as Wiskott-Aldrich syndrome (WAS),by using a virus to insert a properly functioning gene into the patient's blood cells.This technique for correcting defective genes is ________,a specific type of genetic engineering.

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Question 4

A man with a translocation in a chromosome that does not affect gene function may not realize he has a translocation until he attempts to have a child.Explain how a translocation that does not affect the individual may become problematic during reproduction.

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Question 5

While examining the pedigree of a human female,you discover that she has 44 autosomes and two sex chromosomes,an X and a Y.This may lead you to suspect that there is a mutation within this individual's ________ gene.

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Question 6

Explain how two brothers might have different X chromosomes,but they must share identical Y chromosomes.

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Question 7

An allele that is not expressed in heterozygous carriers is called a(n)________ allele.

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Question 8

What factors make it difficult to study human genetic disorders?

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Question 9

Would a karyotype for a human male be considered normal if it shows 45 autosomes and a single pair of sex chromosomes? Explain your reasoning.

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Question 10

A female who carries on her X chromosomes one copy of a recessive mutated allele and one normal copy is referred to as a genetic ________.

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Question 11

The chromosome on the left of the figure below is chromosome number 5 from the father of a newborn child with cri du chat syndrome.The chromosome on the right is paternal chromosome number 5 in the child.What type of chromosomal abnormality has caused this syndrome in the child? Explain your answer.

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Question 12

Explain how an individual who has both an X and a Y sex chromosome would develop embryologically as a female instead of a male.

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Question 13

Can a male human be a carrier of an X-linked trait? Explain your answer.

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Question 14

Karen and Jared produce three healthy children.The first child is a boy (Daniel)and the next two are girls (Leslie and Alice).Daniel grows up,marries Dana,and they have two children.Their first child is a healthy baby boy and the second is a little girl who is diagnosed with phenylketonuria (PKU).Draw this family's pedigree.

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Question 15

Zoe's parents were both heterozygous for the recessive cystic fibrosis allele.Zoe had cystic fibrosis.The chance that any of Zoe's future siblings will have cystic fibrosis is ________.

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Question 16

A karyotype of a human female reveals a total of 45 chromosomes: 44 autosomes and one sex chromosome.Is this karyotype typical of human females? Explain your reasoning.

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Question 17

A horizontal line directly between a square and a circle in a pedigree indicates that those two individuals are a(n)________ pair.

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Question 18

A parent who is a carrier for the recessive autosomal disorder B has the genotype ________.

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Question 19

A disease caused by an inherited mutation is a ________ disorder.

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Question 20

As shown in the figure below,the number of males born each year with hemophilia ________ the number of males born with Fragile-X syndrome each year.

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Quiz 8: Chromosomes and Human Genetics

An individual who has the genotype XNXn for night blindness is considered a ________ for night blindness.