Question 1

Explain the autoimmune mechanism of myasthenia gravis (MG).

Accepted Answer

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Question 2

Describe how the lymphocyte development in the thymus minimizes T cells capable of inducing autoimmunity while maintaining T cells capable of recognizing foreign antigens.

Accepted Answer

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Question 3

Explain how hematopoietic malignancies cause immunosuppression and how many treatments for malignancies also cause immunosuppression.

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Question 4

Discuss how circulating immune complexes are formed in systemic lupus erythematosus (SLE), where they deposit, how tissue is destroyed, and how this relates to the cluster of symptoms associated with SLE.

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Question 5

There are many defects that result in severe combined immunodeficiency disorder. List four and briefly define them.

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Quiz 8: Autoimmune Diseases and Immunodeficiency Disorders

Explain the autoimmune mechanism of myasthenia gravis (MG).

Describe how the lymphocyte development in the thymus minimizes T cells capable of inducing autoimmunity while maintaining T cells capable of recognizing foreign antigens.

Explain how hematopoietic malignancies cause immunosuppression and how many treatments for malignancies also cause immunosuppression.

Discuss how circulating immune complexes are formed in systemic lupus erythematosus (SLE), where they deposit, how tissue is destroyed, and how this relates to the cluster of symptoms associated with SLE.

There are many defects that result in severe combined immunodeficiency disorder. List four and briefly define them.