Question 1

One of the things affecting drug distribution is the bioavailability of the drug.Which of the following factors may affect the amount of a drug that reaches the systemic circulation? Select
All that apply.

Accepted Answer

The solubility of the drug affects its absorption and bioavailability. The route of administration determines how much of the drug reaches systemic circulation, as different routes have different absorption rates and barriers.

Question 2

Which of the following is most affected by pharmacokinetic change?

Accepted Answer

B

Question 3

Which of the following factors affect drug absorption? Select all that apply.

Accepted Answer

A) Metabolic diseases can affect the body's ability to absorb drugs due to alterations in metabolism. B) Esophageal erosion can impact drug absorption by affecting the drug's passage into the stomach. D) Drug-food interactions can either enhance or inhibit the absorption of certain medications, depending on the nature of the interaction.

Question 4

Biotransformation means chemical alteration of things such as nutrients, amino acids, toxins, and drugs in the body.In which organ does biotransformation occurs?

Accepted Answer

The liver is the primary site for the biotransformation of substances, including nutrients, amino acids, toxins, and drugs, making it crucial for detoxification and metabolism.

Question 5

A patient is started on a low dose of a drug for safety but is never advanced to a therapeutic dose while another drug is added.Which of the following does this describe?

Accepted Answer

Clinical inertia refers to the failure to intensify treatment in a timely manner according to evidence-based guidelines. In this scenario, not advancing the dose of a drug to a therapeutic level and instead adding another drug can be an example of clinical inertia, where there is a lack of appropriate adjustment of therapy to reach target goals.

Question 6

Which of the following is true regarding STOPP/START criteria for prescribing medications? Select all that apply.

Accepted Answer

The answer of Which of the following is true regarding...

Question 7

The aging process may alter the dynamic processes that drugs undergo to produce therapeutic effects.Which of the following are terms that refer to these changes? Select all that apply.

Accepted Answer

Pharmacodynamics refers to the effects of drugs on the body, including how drugs exert their therapeutic effects, which can be altered by aging. Pharmacokinetics involves the movement of drugs within the body, including absorption, distribution, metabolism, and excretion, all of which can also be affected by the aging process.

Question 8

Initial and ongoing assessment should be the protocol when prescribing medications. Designating and training office staff to do the initial medication review can save time but still
Requires review by the provider.Which of the following terms refers to a patient bringing in all
Current medications for review?

Accepted Answer

The term "Brown bag" refers to a practice where patients are asked to bring all their current medications in a bag (often literally a brown bag) to a healthcare appointment for review. This helps healthcare providers assess medication adherence, identify potential drug interactions, and make necessary adjustments to the patient's medication regimen.

Question 9

It is important to know the pharmacodynamic influences of the drug.Which of the following statements are true regarding pharmacodynamics? Select all that apply.

Accepted Answer

Pharmacodynamics involves the study of the effects of drugs at their site of action and the relationship between drug concentration and effect, including the time and intensity of the drug effect.

Question 10

Which of the following is related to the incidence of gastric acidity declining with age because of decreased intestinal blood flow?

Accepted Answer

Drug absorption can be affected by changes in gastric acidity, which can decline with age due to decreased intestinal blood flow, potentially altering the solubility and absorption rate of certain medications.

Question 11

A patient sees the nurse practitioner for a post-hospitalization follow-up and presents new complaints with change in functional status.Which of the following should the nurse practitioner do? Select all that apply.

Accepted Answer

A) Evaluating for Adverse Drug Reactions (ADR) is crucial when a patient presents with new complaints or changes in functional status, as these could be side effects of medications. C) Consulting current resources for precautions before prescribing ensures that any new medications do not interact negatively with the patient's current medications or conditions.

Question 12

There are over 35 assessment tools currently available to assist providers with the prescribing of medications.Which of the following consists of a list of potentially inappropriate medications (PIMs)to be avoided in older adults?

Accepted Answer

The Beers Criteria is a list of potentially inappropriate medications (PIMs) to be avoided in older adults, designed to improve the safety of prescribing medications for older adults by reducing the risk of adverse drug events.

Question 13

Polypharmacy is a primary predictor for any undesired or unwanted consequences that can occur because of taking medications.Which is of the following is the correct term for these undesired or unwanted consequences?

Accepted Answer

Adverse drug reaction (ADR) is the correct term for these undesired or unwanted consequences.

Question 14

After consultation with the patient, which of the following is prevented by prescribing only necessary drugs?

Accepted Answer

Polypharmacy, the use of multiple drugs by a patient, is often unnecessary and can lead to negative health outcomes, including adverse drug reactions and increased risk of drug interactions. Prescribing only necessary drugs helps to prevent this issue.

Question 15

Drug distribution in the body is affected by aging and higher body fat.Which of the following is true regarding drugs distributed in fat? Select all that apply.

Accepted Answer

The answer of Drug distribution in the body is affected...

Quiz 17: Polypharmacy

One of the things affecting drug distribution is the bioavailability of the drug.Which of the following factors may affect the amount of a drug that reaches the systemic circulation? Select All that apply.