Which of the following mechanisms are responsible for the possible association between oligohydramnios and lung hypoplasia?
I. Abnormal carbohydrate metabolism
II. Mechanical restriction of the chest wall
III. Interference with fetal breathing
IV. Failure to produce fetal lung liquid

Question

Quizplus · Accepted Answer

Oligohydramnios, a reduced quantity of amniotic fluid present for an extended period of time, with or without renal anomalies, is associated with lung hypoplasia. The mechanisms by which amniotic fluid volume influences lung growth remain unclear. Possible explanations for reduced quantity of amniotic fluid include mechanical restriction of the chest wall, interference with fetal breathing, or failure to produce fetal lung liquid. These clinical and experimental observations possibly point to a common denominator, lung stretch, as being a major growth stimulant.

Which of the Following Mechanisms Are Responsible for the Possible