A 50-Year-Old Woman Reports Pain in One Knee Upon Awakening

A 50-year-old woman reports pain in one knee upon awakening each morning that goes away later in the morning. A knee radiograph is negative for pathology and serum inflammatory markers are normal. What will the provider tell this patient?

A) A magnetic resonance imaging study is necessary for diagnosis
B) That the lack of findings indicates no disease process
C) To take acetaminophen 1 gram three times daily for pain
D) To use a cyclooxygenase 2-selective NSAIDs to reduce inflammation