Question 1

X-linked hyper IgM syndrome (XHIM) is an immunodeficiency disorder caused by mutations of the gene encoding CD154. Why is this disease characterized by recurrent infections (starting in childhood) and elevated serum levels of IgM?

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Question 2

Would taking probiotic health supplements be good for the average person's immunity?

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Question 3

Systemic lupus erythematosus (SLE) is a chronic, inflammatory autoimmune disorder affecting the skin, joints, kidneys, and other organs. A hallmark of lupus is the production of an array of autoantibodies. Some scientists believe that the autoantibody formation seen in lupus is a result of Epstein-Barr virus molecular mimicry. What do these scientists believe has happened in the case of lupus? Give one example as evidential support.

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Question 4

Detail the benefits and predict possible risks of vaccinations.

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Question 5

Why are antihistamines good for allergic rhinitis but not for atopic asthma?

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Question 6

Would treating a person infected with human immunodeficiency virus (HIV) who has recently developed acquired immunodeficiency syndrome (AIDS) using a helper T-cell transfusion work? Why or why not?

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Question 7

Using the information presented in the table below, discuss why most vaccines are given between birth and 24 months.

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Question 8

If a person was unable to undergo negative selection during T-cell education, what is T-cell education, and why would this be a severe immune problem?

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Question 9

List the steps for the classical complement cascade. Discuss two ways this cascade results in microbial destruction.

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Question 10

A patient presents in the emergency room with large red lesions up and down his arms. His case history reveals that he works for a gardening company, and that this rash most likely developed after clearing a weedy bank two days prior. The resident on duty concludes that the rash is a result of poison ivy exposure. Immunologically speaking, what is going on in this man's body, and what type of immune response is he experiencing?

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Quiz 24: The Adaptive Immune Response