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A 42-Year-Old Woman Comes to the Physician Before Undergoing Tooth

Question 21

Multiple Choice

A 42-year-old woman comes to the physician before undergoing tooth extraction.  She recently saw a dentist for lower jaw pain and was told that she needs extraction of a left lower molar.  She has a past history of rheumatic heart disease and had mitral valve replacement at 35 years of age with a mechanical valve.  She moved to the United States from the Philippines 3 years ago.  Her past medical history is otherwise unremarkable.  She takes warfarin daily and has been taking amoxicillin for the past 7 days for presumed "tooth infection."
Physical examination reveals crisp opening and closing clicks of a mechanical prosthetic mitral valve.  No abnormal murmurs are heard.  Her last INR was 2.6.
Which of the following is the most appropriate management for this patient?


A) Continue warfarin and proceed with dental extraction
B) Hold warfarin, give subcutaneous vitamin K, and proceed with dental extraction
C) Hold warfarin until INR is < 1.5, bridge with subcutaneous enoxaparin, and proceed with dental extraction
D) Hold warfarin, wait until INR is < 1.5, and proceed with dental extraction
E) Hold warfarin, wait until INR is < 2.0, and proceed with dental extraction

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