A 26-year-old woman and her spouse visit the office for genetic counseling. She is expecting their second kid, the gender of which is unknown. Both parents are asymptomatic, but their 3-year-old boy suffers from anemia, jaundice, and severe swelling of the hands and feet on a regular basis. A blood sample is taken from the youngster, and hemoglobin electrophoresis at alkaline pH is done. The outcomes are depicted in the graphic below. What is the probability that the unborn child will inherit one or more mutant alleles from the parents?

Question

A 26-year-old woman and her spouse visit the office for genetic counseling. She is expecting their second kid, the gender of which is unknown. Both parents are asymptomatic, but their 3-year-old boy suffers from anemia, jaundice, and severe swelling of the hands and feet on a regular basis. A blood sample is taken from the youngster, and hemoglobin electrophoresis at alkaline pH is done. The outcomes are depicted in the graphic below.  What is the probability that the unborn child will inherit one or more mutant alleles from the parents?

Quizplus · Accepted Answer

Eductional Objective: Sickle cell anemia is an autosomal recessive disorder characterized by recurring bouts of anemia, jaundice, and severe swelling of the hands and feet. Offspring of carriers have a 25% probability of being afflicted and a 50% chance of being heterozygous carriers, for a 75% chance of receiving at least one mutant allele.

A 26-Year-Old Woman and Her Spouse Visit the Office for Genetic