A pharmaceutical company researching novel therapeutic agents for the treatment of Burkitt lymphoma creates a 21-base pair double-stranded RNA molecule. The RNA molecule has a base pair sequence that is complementary to an mRNA region that encodes c-Myc. When the RNA molecule is introduced into tumor cells, cell proliferation is significantly reduced. The results of a Western blot examination of equal numbers of treated and untreated cells are displayed below. Which of the following processes was most likely directly interrupted in the cells exposed to the RNA molecule?

Question

A pharmaceutical company researching novel therapeutic agents for the treatment of Burkitt lymphoma creates a 21-base pair double-stranded RNA molecule. The RNA molecule has a base pair sequence that is complementary to an mRNA region that encodes c-Myc. When the RNA molecule is introduced into tumor cells, cell proliferation is significantly reduced. The results of a Western blot examination of equal numbers of treated and untreated cells are displayed below.  Which of the following processes was most likely directly interrupted in the cells exposed to the RNA molecule?

Quizplus · Accepted Answer

Eductional Objective: By base-pairing with complementary sequences inside target mRNA molecules, short non-coding RNA sequences (e.g., microRNA and small interfering RNA) induce posttranscriptional gene silence.

A Pharmaceutical Company Researching Novel Therapeutic Agents for the Treatment