A 2800-g (6-lb 3-oz) male newborn is born at 39 weeks' gestation to a 24-year-old woman, gravida 2, para 2, after uncomplicated labor and delivery. The mother did not receive prenatal care. She traveled to Brazil to visit relatives during the first trimester of her pregnancy. She has bipolar disorder treated with lithium. The newborn is at the 50th percentile for height, 25th percentile for weight, and 2nd percentile for head circumference. Neurologic examination shows spasticity of the upper and lower extremities. The wrists are fixed in flexion bilaterally. Deep tendon reflexes are 4+ and symmetric. Ophthalmoscopic examination shows focal pigmentary retinal mottling. Testing for otoacoustic emissions is negative. Which of the following viruses most likely caused this patient's in utero infection?

Question

Quizplus · Accepted Answer

Eductional Objective: Zika virus is a single-stranded RNA virus that infects fetal neural progenitor cells, causing severe congenital malformations (eg, microcephaly, arthrogryposis), cerebral cortical thinning, and possible fetal demise.

A 2800-G (6-Lb 3-Oz) Male Newborn Is Born at 39