A 48-year-old woman comes to the hospital due right abdominal pain which radiates to the right shoulder. She has a hsitory of recurrent same episodes but this one is more painful than before and the pain is graded 6/10 in intesity. She has a history of crohns disease for which she takes infliximab. Vital signs and abdominal examination are normal. Abdominal ultrasonography reveals multiple mobile calculi within the gallbladder. Which of the following processes is most likely responsible for the development of gallstones in this patient?

Question

A 48-year-old woman comes to the hospital due right abdominal pain which radiates to the right shoulder. She has a hsitory of recurrent same episodes but this one is more painful than before and the pain is graded 6/10 in intesity. She has a history of crohns disease for which she takes infliximab. Vital signs and abdominal examination are normal.  Abdominal ultrasonography reveals multiple mobile calculi within the gallbladder.  Which of the following processes is most likely responsible for the development of gallstones in this patient?

Quizplus · Accepted Answer

Eductional Objective: Patients with Crohn disease affecting the terminal ileum (most common site of involvement) are prone to developing gallstones.  Decreased bile acid reabsorption by the inflamed terminal ileum promotes cholesterol supersaturation of the bile, resulting in gallstone formation

A 48-Year-Old Woman Comes to the Hospital Due Right Abdominal