A 65-Year-Old Woman Arrives at the Emergency Department Complaining of Left

A 65-year-old woman arrives at the emergency department complaining of left leg pain and swelling that has been bothering her for the past day. She has not experienced any trauma or fever. The patient has a history of high blood pressure, congestive heart failure, type 2 diabetes, and osteoporosis. Her mother and sister both had breast cancer in their families. She is on several medications. The temperature is 37.8 ° C. (100 degrees F) , the blood pressure is 130/80 mm Hg, and the pulse rate is 99 beats per minute. On ambient air, pulse oximetry shows 98 percent. Auscultation reveals clear lungs and normal heart sounds without murmur. Tenderness and edema are present in the left lower extremity up to the mid thigh. An occluding thrombus in the left femoral and popliteal veins is revealed by venous Doppler ultrasonography. Which of the following pharmacotherapies most likely contributed to this patient's current condition?

A) Alendronate
B) Chlorthalidone
C) Empagliflozin
D) Liraglutide
E) Raloxifene
F) Sacubitril-valsartan
G) Spironolactone