A study is being carried out to determine the effect of parathyroid hormone (PTH) on bone remodeling. Half of the study participants receive intermittent PTH injections, while the other half receive a continuous PTH infusion. The findings show that intermittent PTH injections have different effects on bone metabolism than continuous infusion. . Which of the following is most likely to be the predominant bone effect with intermittent injections?

Question

A study is being carried out to determine the effect of parathyroid hormone (PTH) on bone remodeling. Half of the study participants receive intermittent PTH injections, while the other half receive a continuous PTH infusion. The findings show that intermittent PTH injections have different effects on bone metabolism than continuous infusion. .  Which of the following is most likely to be the predominant bone effect with intermittent injections?

Quizplus · Accepted Answer

Eductional Objective: PTH (parathyroid hormone) is released in a pulsatile and continuous/tonic pattern. Continuously elevated PTH levels cause excessive calcium release from bones, increasing the risk of osteoporosis; however, pulsatile secretion has an anabolic effect on bone metabolism, stimulating osteoblast proliferation and inducing increased bone formation.

A Study Is Being Carried Out to Determine the Effect