A 48-year-old woman comes to the emergency department due increase back pain. She is a marathon runner and 2 days agoo she felt down on her back during exercise session. she has no prior medical disease. The patient's last menstrual period was two years ago. Her diet consists mainly of vegetables and fruit, and she takes a daily multivitamin. Her mother died of breast cancer at age 50. Physical examination show back pain with tenderness and normal lower extremities findings. A vertebral stress fracture diagnosed via x-ray. Which of the following drugs is the most appropriate option for decreasing the risk of both bone fractures and breast cancer in this patient?

Question

Quizplus · Accepted Answer

Eductional Objective: In postmenopuse patient with decrease bone density and a family history of breast cancer, a raloxifene has estrogen agonist activity on bone, which decreases bone resorption and improves bone density. on the other hand, Raloxifene has an estrogen antagonist effect on breast tissue and can decrease the risk of breast cancer; with decrease endometrial cancer due to estrogen antagonist in the uterus.

A 48-Year-Old Woman Comes to the Emergency Department Due Increase