Studies That Fail to Establish Significant Benefits of an Intervention

Studies that fail to establish significant benefits of an intervention like medication are often never submitted for publication and instead filed away. The problem with this approach is that

A) only positively-biased data reaches researchers and consumers.
B) files stored on computers can be corrupted.
C) files stored in file drawers can catch fire and burn.
D) files can be lost and data rendered irretrievable.