Which of the Following Characteristics Would Be Expected of the Asthma

Which of the following characteristics would be expected of the asthma of a patient with severe persistent asthma?

A) Asthma attacks are brief of varied intensity, occurring no more than twice a week. Normal peak expiratory flow rate is maintained between attacks. Nighttime symptoms are no more than twice a month.
B) Exacerbations of symptoms affect activity, occurring more than twice a week. Daily short-acting bronchodilator use is prescribed. Nighttime symptoms are more than twice a month.
C) Continual symptoms of asthma that limit physical activities. Frequent exacerbations do not quickly respond to treatments.
D) An acute exacerbation of asthma that does not respond to routine therapies like bronchodilators.