A65-year-old man with a history of prostatic disease was found on radiographic examination of his skeleton to have extensive carcinomatous metastases in his skull and lumbar vertebrae. His PAS levels in his blood were very much higher than normal. Using your knowledge of anatomy, can you suggest a possible route taken by the cancer cells as they migrated from the prostate to (1) the lumbar vertebrae and (2) the skull?
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