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A 14-Year-Old Boy Is Diagnosed with Epidermolysis Bullosa Simplex (EBS)

Question 10

Multiple Choice

A 14-year-old boy is diagnosed with epidermolysis bullosa simplex (EBS) . His skin blisters easily with rubbing or scratching. Blisters occur primarily on his hands and feet and heal without leaving scars. Genetic analysis shows mutations in the KRT5 and KRT14 genes, which code keratin 5 and keratin 14 . What is the primary function of those proteins?


A) Generate movement
B) Provide mechanical stability
C) Carry out nucleation of microtubules
D) Stabilize microtubules against disassembly
E) Transport organelles within the cell

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