A 39-year-old man undergoing an extensive series of tests for infertility is found to have a genetic mutation preventing formation of a functional synaptonemal complex during meiosis, causing almost complete failure of sperm formation. Which cells would be directly affected by this mutation?

Question

Quizplus · Accepted Answer

The synaptonemal complex is crucial for homologous chromosome pairing during meiosis I, which occurs in primary spermatocytes. A mutation affecting this process would directly impact primary spermatocytes, preventing them from progressing through meiosis.

A 39-Year-Old Man Undergoing an Extensive Series of Tests for Infertility