A 38-year-old male patient with a duodenal ulcer is treated successfully with the drug cimetidine. The basis for cimetidine's inhibition of gastric $\mathrm{H}^{+}$ secretion is that it

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IIV B 3 c, d (1), 6]. Cimetidine is a reversible inhibitor of $\mathrm{H}_{2}$ receptors on parietal cells and blocks $\mathrm{H}^{+}$secretion. Cyclic adenosine monophosphate (cAMP) (the second messenger for histamine) levels would be expected to decrease, not increase. Cimetidine also blocks the action of acetylcholine (ACh) to stimulate $\mathrm{H}^{+}$secretion. Omeprazole blocks $\mathrm{H}^{+}, \mathrm{K}^{+}$-adenosine triphosphatase (ATPase) directly.

A 38-Year-Old Male Patient with a Duodenal Ulcer Is Treated H+\mathrm{H}^{+}H+

A 38-Year-Old Male Patient with a Duodenal Ulcer Is Treated $\mathrm{H}^{+}$