A 44-year-old woman is diagnosed with Zollinger-Ellison syndrome. Which of the following findings is consistent with the diagnosis?

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[II A $1 \mathrm{~d} ; \mathrm{VC} 3 \mathrm{~b}$ ]. Zollinger-Ellison syndrome (gastrinoma) is a tumor of the non- $\beta$-cell pancreas. The tumor secretes gastrin, which then circulates to the gastric parietal cells to produce increased $\mathrm{H}^{+}$secretion, peptic ulcer, and parietal cell growth (trophic effect of gastrin). Because the tumor does not involve the pancreatic $\beta$-cells, insulin levels should be unaffected. Absorption of lipids is decreased (not increased) because increased $\mathrm{H}^{+}$secretion decreases the $\mathrm{pH}$ of the intestinal lumen and inactivates pancreatic lipases.

A 44-Year-Old Woman Is Diagnosed with Zollinger-Ellison Syndrome