The mantle bundles are located on the outer area of the nerve membrane and the core bundles are located in the central area. Both have significance in the order of anesthesia development.

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The mantle bundles are located on the outer area of the nerve and are anesthetized first, while the core bundles are located centrally and are anesthetized later, affecting the order of anesthesia development.

The Mantle Bundles Are Located on the Outer Area of the Nerve