Question 1

A 0.5 ´ 0.5 cm lump in the posterior lateral border of the tongue of a 21-year-old man was biopsied. Microscopically, normal-appearing lymphoid tissue was noted in the wall of a benign cystic lesion. This would be consistent with:

Accepted Answer

The presence of normal-appearing lymphoid tissue in the wall of a cystic lesion is characteristic of a lymphoepithelial cyst. The other options are less likely to present with such a finding, as a dermoid cyst would have ectodermal and mesodermal elements, a thyroglossal tract cyst would have remnants of thyroid tissue, squamous cell carcinoma would show malignant squamous epithelial cells, and lymphoma would show malignant lymphoid cells.

Question 2

A 25-year-old woman developed a recurrent mass in her buccal mucosa. On biopsy, the lesion was described as a benign spindle cell proliferation. All the following are consistent with this description except:

Accepted Answer

Benign spindle cell proliferation is not typically associated with lymphoma, which is a malignancy of lymphocytes. The other options are all benign spindle cell proliferations.

Question 3

A 33-year-old patient presents with an asymptomatic swelling of her right submandibular space. Which of the following should be considered in a clinical differential diagnosis?

Accepted Answer

All of the options listed can potentially cause an asymptomatic swelling in the submandibular space. Chronic lymphadenitis can cause a persistent enlargement of lymph nodes, salivary gland tumors can present as painless enlargements, lymphoepithelial cysts can occur in the submandibular space, and lymphoma can present as a painless mass as well. Therefore, all of these options should be considered in the differential diagnosis.

Question 4

Oral extranodal lymphomas are most likely to present as ulcerated or nonulcerated masses in which of the following sites?

Accepted Answer

The answer of Oral extranodal lymphomas are most likely to...

Question 5

A 32-year-old HIV-positive patient developed an ulcerated gingival mass that was biopsied and diagnosed as high-grade lymphoma. A staging workup showed that he had stage IV disease. His prognosis relative to his lymphoma would be:

Accepted Answer

Stage IV high-grade lymphoma has a poor prognosis, and being HIV-positive also decreases the patient's overall chances of successful treatment and survival.

Question 6

Which of the following is seen with increased frequency in AIDS patients?

Accepted Answer

Lymphoma is commonly seen at an increased frequency in AIDS patients due to the immunosuppression caused by the virus.

Question 7

Excluding tonsil, oral extranodal lymphomas are most commonly seen in which of the following sites?

Accepted Answer

Extranodal lymphomas are most commonly seen in palatal region.

Question 8

Oral extranodal lymphomas:

Accepted Answer

Oral extranodal lymphomas can be a manifestation of systemic disease or may represent the primary site of the disease. They are rarely of the Hodgkin's type and usually present as masses or ulcerated masses.

Question 9

Oral extranodal lymphomas that are HIV related are most commonly of which of the following types?

Accepted Answer

HIV-related oral extranodal lymphomas are most commonly of high-grade B-cell lymphomas, such as diffuse large B-cell lymphoma.

Quiz 9: Lymphoid Lesions