Which of the following assays would be most appropriate for monitoring minimal residual disease?

Question

Quizplus · Accepted Answer

PCR (polymerase chain reaction) is the most sensitive and specific method for monitoring minimal residual disease. It can detect very small amounts of residual disease by amplifying specific DNA sequences. Karyotyping and Southern Blot analysis are less sensitive and specific compared to PCR, and cannot detect minimal residual disease as effectively.

Which of the Following Assays Would Be Most Appropriate for Monitoring