Which one of the following immunosuppressant prodrugs inhibits inosine monophosphate dehydrogenase (IMPDH)to reduce the pool of intracellular guanine nucleotides and arrest T-cell proliferation?

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Mycophenolate mofetil is a prodrug that is converted into mycophenolic acid, which inhibits the enzyme IMPDH. This results in reduction of intracellular guanine nucleotides and inhibition of T-cell proliferation. Tacrolimus inhibits calcineurin, while disopyramide and imipramine are not used as immunosuppressant drugs.

Which One of the Following Immunosuppressant Prodrugs Inhibits Inosine Monophosphate