When is fluorescence in situ hybridization (FISH)most likely to be used?

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FISH is most commonly used to detect chromosomal abnormalities, such as trisomy 13 in a stillborn infant. It can also be used for other chromosomal abnormalities, such as translocations or deletions. It is not typically used to find a specific gene associated with a disease or determine carrier status for a genetic disorder. In the case of possible adult-onset single gene disorders, other genetic testing methods such as sequencing or genotyping are typically used.

When Is Fluorescence in Situ Hybridization (FISH)most Likely to Be