Which of the Following Statements Is True

Which of the following statements is true?

A) Selective toxicity is harder to achieve when developing drugs against eukaryotic pathogens than it is against bacteria.
B) Compared to antibiotics, antifungal drugs usually have limited side effects.
C) To date, drug resistance has not been a problem with antimalarial drugs.
D) Drugs against eukaryotic pathogens generally act by interfering with ribosomes.
E) An advantage of most drugs against eukaryotic pathogens is that they tend to be extremely narrow spectrum.