The formation of hemoglobin in the body requires a balance between heme and globin synthesis. Which statement below best describes how this balance is maintained?

Question

Quizplus · Accepted Answer

The balance between heme and globin synthesis is maintained through the feedback inhibition mechanism where hemin (the oxidized form of heme) inhibits the enzyme ALA synthase, which is crucial for the first step in heme synthesis. This regulation ensures that heme synthesis is matched with globin synthesis to form functional hemoglobin.

The Formation of Hemoglobin in the Body Requires a Balance