The major regulatory step in the formation of heme by de novo synthesis is

Question

Quizplus · Accepted Answer

Delta-aminolevulinate synthase is the first and rate-limiting enzyme in the de novo synthesis of heme. Therefore, the major regulatory step in the formation of heme is the activity of this enzyme. The other options mentioned are not directly involved in the de novo synthesis of heme. Heme oxygenase is responsible for heme degradation, cytochrome P-450 is a superfamily of enzymes involved in metabolism, and glucuronyl transferase is involved in the conjugation of bilirubin, a byproduct of heme degradation.

The Major Regulatory Step in the Formation of Heme by De