Deck 10: Nutritional Genomics
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Deck 10: Nutritional Genomics
1
During _____, the anticodons from tRNA attach to the mRNA via complementary base pairing
A)meiosis
B)mitosis
C)transcription
D)translation
A)meiosis
B)mitosis
C)transcription
D)translation
D
2
The interaction between nutrients and _____ is known as nutritional genomics
A)the genotype
B)phenotypes
C)the genome
D)genetics
A)the genotype
B)phenotypes
C)the genome
D)genetics
C
3
_____ are small proteins around which DNA is wrapped and can be modified by methylation, acetylation, and phosphorylation
A)Alleles
B)Codons
C)Histones
D)Nucleotides
A)Alleles
B)Codons
C)Histones
D)Nucleotides
C
4
Which of the following disorders are extremely rare, occurring only in males as a result of the inheritance of mutations in the Y chromosome from the father?
A)X-linked disorders
B)X-linked dominant disorders
C)recessive disorders
D)Y-linked disorders
A)X-linked disorders
B)X-linked dominant disorders
C)recessive disorders
D)Y-linked disorders
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5
During _____, DNA unwinds in the area encoding the gene of interest and the code is copied
A)meiosis
B)mitosis
C)transcription
D)translation
A)meiosis
B)mitosis
C)transcription
D)translation
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6
One example of an autosomal recessive trait with nutritional implications is:
A)phenylketonuria.
B)familial hypercholesterolemia.
C)LDL dysfunction.
D)diabetes mellitus.
A)phenylketonuria.
B)familial hypercholesterolemia.
C)LDL dysfunction.
D)diabetes mellitus.
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7
Which of the following is not a primary component of nucleotides?
A)purine or pyrimidine nitrogenous base
B)carboxyl group
C)ribose
D)phosphate group
A)purine or pyrimidine nitrogenous base
B)carboxyl group
C)ribose
D)phosphate group
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8
Chemicals that are found in an organism but are not produced by it or expected to be there, such as drugs or pollutants, are called:
A)probiotics.
B)prebiotics.
C)antibiotics.
D)xenobiotics.
A)probiotics.
B)prebiotics.
C)antibiotics.
D)xenobiotics.
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9
How many pairs of chromosomes are found in humans?
A)23
B)27
C)13
D)29
A)23
B)27
C)13
D)29
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10
A group of genes that work in concert to produce a specific phenotype is termed a(n):
A)haplotype.
B)geneotype.
C)karyotype.
D)allele.
A)haplotype.
B)geneotype.
C)karyotype.
D)allele.
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11
_____ relates to the pattern of gene expression regulated by modification of DNA
A)The Human Genome Project
B)Genetics
C)Nutrigenomics
D)Epigenetics
A)The Human Genome Project
B)Genetics
C)Nutrigenomics
D)Epigenetics
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12
It has been shown that for those people with an inherited APC gene, which is associated with various GI tract tumors, supplementation of _____ has a protective effect
A)eicosapentaenoic acid
B)omega-6 fatty acids
C)saturated fatty acids
D)soy protein
A)eicosapentaenoic acid
B)omega-6 fatty acids
C)saturated fatty acids
D)soy protein
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13
The primary difficulty in predicting the benefits of dietary changes and how they will affect gene expression is:
A)not everyone eats the same.
B)not everyone responds the same to environmental exposures.
C)there is a great variety of intake from supplements currently.
D)There is no difficulty in predicting the benefits.
A)not everyone eats the same.
B)not everyone responds the same to environmental exposures.
C)there is a great variety of intake from supplements currently.
D)There is no difficulty in predicting the benefits.
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14
The process of cell reproduction where only one member of each pair of chromosomes is passed on is termed:
A)meiosis.
B)mitosis.
C)karyotype.
D)the human genome project.
A)meiosis.
B)mitosis.
C)karyotype.
D)the human genome project.
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15
The genetic material lies within each nucleus of each cell in the body except:
A)cells of the liver.
B)cells of the skin.
C)RBC.
D)lymphoid tissue.
A)cells of the liver.
B)cells of the skin.
C)RBC.
D)lymphoid tissue.
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16
The recent advent of _____ technology permits large-scale exploration of the effects of diet on the expression of thousands of genes
A)allele
B)immunoassay
C)microarray
D)genetic testing
A)allele
B)immunoassay
C)microarray
D)genetic testing
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17
The interaction between drugs and an individual's genome is called:
A)nutrigenomics.
B)genotyping.
C)phenotyping.
D)pharmacogenomics.
A)nutrigenomics.
B)genotyping.
C)phenotyping.
D)pharmacogenomics.
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18
Prader-Willi syndrome is best described as an error in:
A)genotype.
B)genomic imprinting.
C)metabolism.
D)the number of nucleotides.
A)genotype.
B)genomic imprinting.
C)metabolism.
D)the number of nucleotides.
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19
One of the greatest challenges for the RD in the emerging field of nutrigenomics is:
A)phenotyping an individual.
B)mapping the genome.
C)individualizing diets and counseling.
D)deciding which chronic diseases to target.
A)phenotyping an individual.
B)mapping the genome.
C)individualizing diets and counseling.
D)deciding which chronic diseases to target.
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20
The process of cell division is termed:
A)meiosis.
B)mitosis.
C)karyotype.
D)the human genome project.
A)meiosis.
B)mitosis.
C)karyotype.
D)the human genome project.
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21
Case Study Multiple Choice
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
The registered dietitian continues to counsel Mrs G on how to reduce the incidence of the type of cancer associated with her polymorphism She recommends that Mrs G consume high amounts of which of the following in order to decrease polyamine production?
A)blueberries and cranberries
B)cauliflower and carrots
C)broccoli and blueberries
D)onions and carrots
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
The registered dietitian continues to counsel Mrs G on how to reduce the incidence of the type of cancer associated with her polymorphism She recommends that Mrs G consume high amounts of which of the following in order to decrease polyamine production?
A)blueberries and cranberries
B)cauliflower and carrots
C)broccoli and blueberries
D)onions and carrots
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22
Case Study Multiple Choice
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
Mr G's genetic profile shows that he has a variation in the codes for apolipoprotein E The registered dietitian counsels him on several ways to lower hyperlipidemia risk, but does not discuss _____ due to its limited research outcomes
A)modifying alcohol consumption
B)increasing physical activity
C)not smoking
D)changing the amount of cholesterol and dietary fat
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
Mr G's genetic profile shows that he has a variation in the codes for apolipoprotein E The registered dietitian counsels him on several ways to lower hyperlipidemia risk, but does not discuss _____ due to its limited research outcomes
A)modifying alcohol consumption
B)increasing physical activity
C)not smoking
D)changing the amount of cholesterol and dietary fat
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23
Case Study Multiple Choice
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
The registered dietitian reads the genetic report and finds that Mrs G has a polymorphism in the methylene tetrahydrofolate reductase gene She counsels Mrs G that this is linked to an increased risk of which of the following?
A)hyperlipidemia
B)colon cancer
C)obesity
D)diabetes
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
The registered dietitian reads the genetic report and finds that Mrs G has a polymorphism in the methylene tetrahydrofolate reductase gene She counsels Mrs G that this is linked to an increased risk of which of the following?
A)hyperlipidemia
B)colon cancer
C)obesity
D)diabetes
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24
A diet high in _____ has been linked to insulin resistance, while a diet high in _____ has been linked to greater insulin sensitivity
A)protein, MUFAs
B)saturated fat, MUFAs
C)MUFAs, saturated fat
D)fiber, saturated fat
A)protein, MUFAs
B)saturated fat, MUFAs
C)MUFAs, saturated fat
D)fiber, saturated fat
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25
Case Study Multiple Choice
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
Should Mrs G decide to supplement with the above nutrient, she should be cautioned that in those with her SNP plus an additional SNP (which she may have), high intakes are associated with higher risk for:
A)cardiovascular disease.
B)diabetes.
C)breast cancer.
D)obesity.
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
Should Mrs G decide to supplement with the above nutrient, she should be cautioned that in those with her SNP plus an additional SNP (which she may have), high intakes are associated with higher risk for:
A)cardiovascular disease.
B)diabetes.
C)breast cancer.
D)obesity.
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26
Recent studies have proven positive effects of _____ and ligands on triglyceride levels and insulin sensitivity
A)PUFAs
B)saturated fats
C)MUFAs
D)animal protein
A)PUFAs
B)saturated fats
C)MUFAs
D)animal protein
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27
_____ intakes of folate have long been associated with cancer risk, and this risk appears to escalate in the presence of _____ intake
A)Low, alcohol
B)High, saturated fat
C)High, alcohol
D)Low, saturated fat
A)Low, alcohol
B)High, saturated fat
C)High, alcohol
D)Low, saturated fat
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28
Case Study Multiple Choice
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
In addition to the recommendations already mentioned, the registered dietitian also recommends that which of the following be limited in Mrs G diet for optimal lowering of risk with this polymorphism?
A)saturated fat
B)cholesterol
C)alcohol
D)weight
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
In addition to the recommendations already mentioned, the registered dietitian also recommends that which of the following be limited in Mrs G diet for optimal lowering of risk with this polymorphism?
A)saturated fat
B)cholesterol
C)alcohol
D)weight
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29
Studies have shown a reduction of colon cancer risk, at least among individuals with certain genotypes, with ingestion of isothiocyanates found in:
A)protein.
B)cruciferous vegetables.
C)oranges.
D)tomatoes.
A)protein.
B)cruciferous vegetables.
C)oranges.
D)tomatoes.
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30
Case Study Multiple Choice
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
The above can be exacerbated by a(n) _____ deficiency; therefore, the registered dietitian will counsel Mrs G on how to achieve optimal levels in her diet
A)omega-3 fatty acids
B)glutamine
C)vitamin B12
D)folate
Mr.and Mrs.G come into an outpatient nutrition counseling center due to referral from their genetic physician.They have both been tested for several genetic conditions due to their family history and concern over developing chronic diseases.Mrs.G is particularly concerned due to the history of cancer in her family on both her mother's and father's sides.
The above can be exacerbated by a(n) _____ deficiency; therefore, the registered dietitian will counsel Mrs G on how to achieve optimal levels in her diet
A)omega-3 fatty acids
B)glutamine
C)vitamin B12
D)folate
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31
Match between columns
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