Deck 1: Introduction to Pharmacology, Pharmacokinetics, Pharmacodynamics, and Drug Regulations

Question 1

The nurse is educating a client who is participating in a drug study and describes the median toxicity dose as the dose that will produce toxicity in ________% of a group of clients.
Record your answer rounding to the nearest whole number.

Answer 1

50

Question 2

The nurse checks the margin of safety (MOS) for a drug that will be administered to a client, knowing that the MOS is the amount of drug that is lethal to ________% of animals divided by the amount that produces a therapeutic effect in ________% of animals.
Record your answer rounding to the nearest whole number.

Answer 2

1, 99

Question 3

The nurse administered an antihypertensive medication to a client with high blood pressure. The nurse assesses the blood pressure and notices that the blood pressure was reduced after administration of the blood pressure medication. Which pharmacologic response is the client experiencing?

A) The therapeutic index
B) The margin of safety
C) The lethal dose
D) The median effective dose

Answer 3

D

Question 4

The nurse has administered a dose of codeine to a client for the management of postoperative pain. The nurse monitors for respiratory depression because ________% of codeine is metabolized and converted to morphine, which can cause respiratory depression in clients.
Record your answer rounding to the nearest whole number.

Question 5

The nurse is teaching a client about the loading dose of antibiotic that will be administered later in the day. The client demonstrates understanding by stating that the medication will reach a therapeutic dose in ________ hour(s) versus the 48 hours that would be required for the routine medication dose.
Record your answer rounding to the nearest whole number.

Question 6

Which is a reason that delayed approval by the Food and Drug Administration (FDA) of newer drugs prior to 1990?

A) The FDA was using outdated guidelines.
B) There was not enough money from the drug companies to support the testing.
C) Drug companies identified a handful of drugs necessary for disease outbreaks.
D) The drug approval process was not supported by the larger federal government sector.

Question 7

Which statement best describes the difference between a biologic drug and a biosimilar drug?

A) Biologic drugs are medications made by living cells.
B) Biosimilar drugs are medications made by cells lysed by other cells.
C) Biologic drugs are not approved by the FDA.
D) Biosimilar drugs are more expensive than biologics.

Question 8

Which statements are characteristics of biosimilar drugs?
Select all that apply.

A) They are FDA approved.
B) They are less expensive.
C) They are made of living cells.
D) They are a duplicate copy of the reference product.
E) They are considered a generic medication.