Deck 1: Characteristics of Different Controlled Release Drug Delivery Systems

Question 1

Oral controlled release drugs release the drug only inside the intestine.

Answer 1

False

Question 2

What are the characteristics of continuous release systems?

A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Release only at a specific drug
D)Release as soon as comes in contact to the saliva

Answer 2

Prolonged their residence in the GIT and release

Question 3

What is the characteristic of delayed transit and continuous release systems?

A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Release only at a specific drug
D)Release as soon as comes in contact to the saliva

Answer 3

Prolonged their residence in the GIT and release

Question 4

What is the characteristic of delayed release systems?

A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Release only at a specific drug
D)Release as soon as comes in contact to the saliva

Question 5

What is the characteristic of dissolution controlled release systems?

A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Release only at a specific drug
D)Very slow dissolution rate

Question 6

What is the characteristic of matrix dissolution-controlled release systems?

A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Release only at a specific drug
D)Employ waxes to control the rate of dissolution

Question 7

What is the characteristic of encapsulation or coating dissolution-controlled release systems?

A)Microencapsulation using slowly dissolving materials
B)Prolonged their residence in the GIT and release
C)Release only at a specific drug
D)Employ waxes to control the rate of dissolution

Question 8

What are the characteristics of diffusion-controlled release systems?

A)Release the drug along the entire length of GIT
B)Diffusion of the dissolved drug
C)Release only at a specific drug
D)Employ waxes to control the rate of dissolution

Question 9

What are the characteristics of Matrix diffusion-controlled release systems?

A)Release the drug along the entire length of GIT
B)Drug disperse in an insoluble matrix of rigid hydrophobic materials
C)Release only at a specific drug
D)Employ waxes to control the rate of dissolution

Question 10

What are the characteristics of reservoir devices-controlled release systems?

A)Release the drug along the entire length of GIT
B)Drug disperse in the insoluble matrix of rigid hydrophobic materials
C)Hollow systems containing drug surrounded by a polymer membrane
D)Employ waxes to control the rate of dissolution

Question 11

What are the characteristics of ion exchange resin drug complexes?

A)Release the drug along the entire length of GIT
B)Drug disperse in an insoluble matrix of rigid hydrophobic materials
C)Hollow systems containing drug surrounded by a polymer membrane
D)Formation of complexes between the drug and anion/cation exchange resins

Question 12

What is the characteristic of pH-independent formulations?

A)Buffering agents that adjust pH to the desired value
B)Drug disperse in the insoluble matrix of rigid hydrophobic materials
C)Hollow systems containing drug surrounded by a polymer membrane
D)Formation of complexes between the drug and anion/cation exchange resins

Question 13

What are the characteristics of osmotic pressure-controlled systems?

A)Buffering agents that adjust pH to the desired value
B)Releases the drug at a zero-order kinetics
C)Hollow systems containing drug surrounded by a polymer membrane
D)Formation of complexes between the drug and anion/cation exchange resins

Question 14

Osmotic pressure controlled systems work on the principle of osmotic pressure releasing the drug at constant 1st order kinetics.

Question 15

What are the characteristics of hydrodynamic pressure controlled systems?

A)Buffering agents that adjust pH to the desired value
B)Drug disperse in an insoluble matrix of rigid hydrophobic materials
C)Generated by swelling hydrophilic hum
D)Formation of complexes between the drug and anion/cation exchange resins

Question 16

What is the characteristics of altered density systems?

A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Release only at a specific drug
D)Use of high or low density pellets

Question 17

What is the characteristics of floating or buoyant capsule systems?

A)Release the drug along the entire length of GIT
B)Granule drug with hydro gel
C)Release only at a specific drug
D)Use of high or low density pellets

Question 18

What is the characteristics of mucoadhesive systems?

A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Usage of bio adhesive polymer
D)Use of high or low density pellets

Question 19

Enteric coating are used for which systems?

A)Intestinal release systems
B)Colonic release systems
C)Size based systems
D)Mucoadhesive systems

Question 20

Drugs cannot be delivered to the colon.

Question 21

What is the characteristics of intestinal release systems?

A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Usage of polymers that dissolves only in the alkaline pH of colon
D)Use of enteric coating

Question 22

What is the characteristics of colonic release systems?

A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Usage of polymers that dissolves only in the alkaline pH of colon
D)Use of enteric coating

Question 23

Liposomes are spherical structures, usually between in diameter:

A)80nm-100nm
B)60nm-100nm
C)55nm-1000nm
D)15nm-1000nm

Question 24

Liposomes consists of a bilayer of

A)Hydrophilic molecules
B)Hydrophobic molecules
C)Both a and b
D)None

Question 25

Liposomes have half life

A)Longer
B)Shorter
C)Intermediate
D)Both a and b