Question 1

Oral controlled release drugs release the drug only inside the intestine.

Accepted Answer

Oral controlled release drugs are designed to release the drug at a predetermined rate in order to maintain a constant drug concentration for a specific period of time, which can involve release in the stomach, intestine, or throughout the gastrointestinal tract, not exclusively in the intestine.

Question 2

What are the characteristics of continuous release systems?

Accepted Answer

B

Question 3

What is the characteristic of delayed transit and continuous release systems?

Accepted Answer

Delayed transit and continuous release systems are designed to prolong the residence time of the drug in the gastrointestinal tract (GIT) and release the drug over an extended period.

Question 4

What is the characteristic of delayed release systems?

Accepted Answer

Delayed release systems are designed to release the drug at a specific site in the gastrointestinal tract, often to target a particular area for absorption or to avoid degradation in the stomach.

Question 5

What is the characteristic of dissolution controlled release systems?

Accepted Answer

Dissolution controlled release systems are characterized by a very slow dissolution rate, which controls the release of the drug over an extended period.

Question 6

What is the characteristic of matrix dissolution-controlled release systems?

Accepted Answer

Matrix dissolution-controlled release systems use waxes or other materials to control the rate at which the drug dissolves, thereby controlling the release rate.

Question 7

What is the characteristic of encapsulation or coating dissolution-controlled release systems?

Accepted Answer

Encapsulation or coating dissolution-controlled release systems use microencapsulation with slowly dissolving materials to control the release rate of the drug.

Question 8

What are the characteristics of diffusion-controlled release systems?

Accepted Answer

Diffusion-controlled release systems rely on the diffusion of the dissolved drug through a polymer matrix or membrane to control the release rate.

Question 9

What are the characteristics of Matrix diffusion-controlled release systems?

Accepted Answer

Matrix diffusion-controlled release systems involve the dispersion of the drug in an insoluble matrix made of rigid hydrophobic materials, which controls the release rate by diffusion.

Question 10

What are the characteristics of reservoir devices-controlled release systems?

Accepted Answer

Reservoir devices-controlled release systems are characterized by having a core of the drug (the reservoir) which is then surrounded by a rate-controlling membrane made of polymers. This design allows for a controlled release of the drug over time. Choices A, B, and D describe other types of controlled release systems, not specifically reservoir devices.

Question 11

What are the characteristics of ion exchange resin drug complexes?

Accepted Answer

Formation of complexes between the drug and anion/cation exchange resins

Question 12

What is the characteristic of pH-independent formulations?

Accepted Answer

The answer of What is the characteristic of pH-independent formulations?
...

Question 13

What are the characteristics of osmotic pressure-controlled systems?

Accepted Answer

The answer of What are the characteristics of osmotic pressure-controlled...

Question 14

Osmotic pressure controlled systems work on the principle of osmotic pressure releasing the drug at constant 1st order kinetics.

Accepted Answer

Osmotic pressure controlled systems release the drug at a rate that is zero-order kinetics, not first-order, meaning the drug is released at a constant rate independent of its concentration.

Question 15

What are the characteristics of hydrodynamic pressure controlled systems?

Accepted Answer

Hydrodynamic pressure controlled systems typically involve the generation of pressure through the swelling of hydrophilic gums. When these gums come into contact with water or bodily fluids, they swell, creating a pressure that can help control the release of the drug from the system.

Question 16

What is the characteristics of altered density systems?

Accepted Answer

The answer of What is the characteristics of altered density...

Question 17

What is the characteristics of floating or buoyant capsule systems?

Accepted Answer

The answer of What is the characteristics of floating or...

Question 18

What is the characteristics of mucoadhesive systems?

Accepted Answer

Mucoadhesive systems use bioadhesive polymers to prolong their residence in the GIT and release the drug along the entire length of GIT.

Question 19

Enteric coating are used for which systems?

Accepted Answer

Enteric coatings are designed to prevent the release of medication before it reaches the intestines, making them suitable for intestinal release systems.

Question 20

Drugs cannot be delivered to the colon.

Accepted Answer

Drugs can be delivered to the colon using specific formulations and technologies designed to bypass the stomach and small intestine, ensuring the drug is released in the colon for local or systemic effects.

Quiz 1: Characteristics of Different Controlled Release Drug Delivery Systems