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Why Is the Additional (Ring)nitrogen in Tryptophan Not Very Basic

Question 5

Multiple Choice

Why is the additional (ring) nitrogen in tryptophan not very basic? Why is the additional (ring) nitrogen in tryptophan not very basic?   A)  Cyclic amines are not basic. B)  It is too far from the carboxyl group to be effected. C)  Aromatic amines are weakly basic because of resonance. D)  The additional amine group is offset by an additional carboxylic acid group. E)  It is sp<sup>2</sup> hybridized as therefore not as basic.


A) Cyclic amines are not basic.
B) It is too far from the carboxyl group to be effected.
C) Aromatic amines are weakly basic because of resonance.
D) The additional amine group is offset by an additional carboxylic acid group.
E) It is sp2 hybridized as therefore not as basic.

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