Prolonged or Excessive Use of Antacids Should Be Avoided Because

Prolonged or excessive use of antacids should be avoided because:

A) these drugs can alter the metabolism of other drugs that rely on gastric acidity to activate the drug.
B) these drugs can affect the elimination of other drugs by altering urinary pH.
C) acid production may increase (acid rebound) when these drugs are suddenly discontinued.
D) all of the above
E) none of the above