Antidepressant drugs that selectively affect 5-hydroxytryptamine (serotonin)neurotransmission may also cause "serotonin syndrome" which is characterized by:

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Serotonin syndrome is characterized by all of the above symptoms, including sweating, shivering, movement disorders, muscle fasciculations, and more severe symptoms such as fever, seizures, and even death in extreme cases. Selective serotonin reuptake inhibitors (SSRIs) are a common class of antidepressant drugs that can cause serotonin syndrome in combination with other medications or supplements that increase serotonin levels. It is important to be aware of the signs and symptoms of serotonin syndrome and seek medical attention immediately if they occur.

Antidepressant Drugs That Selectively Affect 5-Hydroxytryptamine (Serotonin)neurotransmission May Also Cause