Cytotoxic lymphocytes are activated by recognition and binding of antigen in association with major histocompatibility complex type I (MHC I) proteins.

Question

Quizplus · Accepted Answer

This is true. Cytotoxic lymphocytes, such as CD8+ T cells and natural killer (NK) cells, identify and bind to antigens presented on the surface of infected or abnormal cells in association with MHC I proteins. This recognition triggers the cytotoxic lymphocytes to release substances that destroy the target cell, helping to eliminate pathogens and cancerous cells from the body.

Cytotoxic Lymphocytes Are Activated by Recognition and Binding of Antigen