What is the main reason that metformin does not usually cause hypoglycemia in patients with T2DM?

Question

Quizplus · Accepted Answer

Metformin decreases glucose production in the liver by inhibiting gluconeogenesis, which is the process by which the liver produces glucose from non-carbohydrate sources such as amino acids and fatty acids. This action does not stimulate insulin release from beta cells or suppress glucagon production, which are the mechanisms that can lead to hypoglycemia. Additionally, metformin does not affect the inactivation of peptide 1 and dipeptidyl-peptidase 4, which are involved in incretin hormone metabolism and have no direct impact on glucose production.

What Is the Main Reason That Metformin Does Not Usually