By the time the filtrate reaches the tip of the renal pyramid, the concentration of the filtrate is higher than the concentration of the interstitial fluid.

Question

Quizplus · Accepted Answer

As the filtrate moves down the descending limb of the loop of Henle into the renal pyramid, it becomes more concentrated due to water reabsorption. However, the interstitial fluid in the medulla, which surrounds the loop, is even more concentrated due to the counter-current multiplier system, ensuring efficient reabsorption of water and salts.

By the Time the Filtrate Reaches the Tip of the Renal