A 22-year-old male presents with difficulty swallowing. Tests reveal a loss of esophageal peristalsis and failure of the lower esophageal sphincter to relax. Which of the following is the most likely cause?
A) Neurologic dysfunction
B) Intrinsic mechanical obstruction
C) Extrinsic mechanical obstruction
D) Smooth muscle hyperplasia

Question

Quizplus · Accepted Answer

The loss of esophageal peristalsis and failure of the lower esophageal sphincter to relax suggest a neurological dysfunction, most likely achalasia. Intrinsic mechanical obstruction and smooth muscle hyperplasia would typically present with more focal symptoms, while extrinsic mechanical obstruction would typically present with difficulty swallowing solids rather than liquids.

A 22-Year-Old Male Presents with Difficulty Swallowing