In which of the following conditions would the pancreas be unable to synthesize insulin?

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Type 1 diabetes mellitus is caused by the destruction of the cells in the pancreas that produce insulin, leading to an inability to synthesize insulin. Hyperglycemia and hypoglycemia are both conditions of abnormal blood sugar levels, but the pancreas may still be able to synthesize insulin in these cases. In type 2 diabetes mellitus, the body becomes resistant to insulin and may not respond to it effectively, but the pancreas can still synthesize insulin.

In Which of the Following Conditions Would the Pancreas Be