A phenotypically normal woman marries a man with CMT disease,an autosomal dominant disorder.They have a son who has CMT disease.What were the chances he would get the disease? (Draw a Punnett square to help you determine the answer. )

Question

Quizplus · Accepted Answer

Since CMT is autosomal dominant, the affected father has one dominant allele (C) and one recessive allele (c). The phenotypically normal mother has two recessive alleles (cc). The Punnett square shows a 2:4 (or 1:2) chance for the son to inherit the disease (Cc).

A Phenotypically Normal Woman Marries a Man with CMT Disease,an